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Properties of the malarial proteins Pf2, Pf9 and PfP0, which support their roles as immune targets
- Antibodies raised to each of these proteins (or purified from immune adults) inhibit the growth of Plasmodium falciparum at the red cell invasion step.
- The proteins are localized on the parasite cell surface.
- Each protein is conserved in several species of malarial parasite
- Passive immunization of purified IgG raised against these protein, protects mice against lethal murine malarial parasites.