Severe Acute Respiratory Syndrome- SARS
Global pattern of SARS epidemic
SARS – clinical features
Radiological features of lungs-showing progression of disease
cT Scan of SARS lungs
SARS – Lung Pathology
SARS - Diagnosis
How did SARS spread ?
Economics of Epidemics -SARS
How was SARS contained so fast ?
Phylogenetic tree of coronaviruses-May 2003
SARS- urbani strain genome Rota et al Scienceexpress, May 2003
Sequence homology of corona viruses from mammalian species
ToR strain genome Marra et al, sciencexpress, May 2003
Three dimensional structure of human coronavirus main proteinase (Mpro) which regulates replication
Dimer of HCoV Mpro
Inhibitors of TGEV Mpro bind to Mpros of other species
Antirhinoviral drug should inhibit SARS virus MPro
SARS – Koch´Postulates proved.
SARS – virus jumps species
How infectious is SARS virus
SARS – Global Distribution- 10th July 2003
Epidemics – What do we learn ?
Politics of epidemics - SARS
SARS and other Epidemics
SARS – Unprecedented international efforts
Severe Acute Respiratory Syndrome- SARS 2003
Dr. Carlos Urbani dies during SARS investigations