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SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL APPROACH TO EXPLORE UNTAPPED BACTERIAL DIVERSITY

UNDER GRADUATE RESEARCH An alternative model of doing science

THE EXPANSE OF LIFE

HOW MANY SP. OF BACTERIA IN 1 g SOIL? TORSVIK ET AL 1990

Culture Independent Molecular (CIM) approach A SIGNIFICANT DEVIATION FROM CLASSICAL MICROBIOLOGY

UNCULTURABLE BACTERIA A NON-CONCEPT

THE REALIZATION IS NOT NEW

Microcolonies on oligotrophic medium

COUNT DIFFERENCES

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ACCUMULATION OF COLONIES ON PROLONGED INCUBATION

DNA REASSOCIATION RATES THE TOTAL OLIGOPHILE DNA DIVERSITY CLOSE TO TOTAL HABITAT DNA

THE NEAREST SEQUENCE MATCH OF OLIGOPHILIC ISOLATES

PowerPoint Presentation

CULTIVATING THE UNCULTIVABLE Japanese macaques at work

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COPIOTROPHY ADAPTATION FREQUENCY DISTRIBUTION OF MUTANTS IN A LURIA-DELBRUCK EXPERIMENT

A BACTERIAL CYTOKINE Mukamolova et al (1998) PNAS, 95, 8916-8921

BACK TO OLIGOPHILY ISOLATES ADAPTED TO COPIOPHILY REVERT IN THE NATURAL HABITAT

REDUCTION IN GROWTH YIELD WITH INCREASING SUBSTRATE CONCENTRATION

GROWTH YIELDS

OLIGOPHILE GROWTH YIELDS REACH (EXCEED?) THE THEORETICAL MAXIMUM

GROWTH YIELDS GROWTH RATES

A METABOLIC WASTAGE MODEL FOR THE RATE-YIELD TRADE OFF

TRADE OFF BETWEEN GROWTH RATE AND GROWTH YIELD

SITTING ON A GOLDMINE

QUESTIONS TO BE ADDRESSED

UNANSWERABLE QUESTIONS JUST AS INTERESTING AS UNCULTURABLE BACTERIA!

CREDITS

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