• S Kasinathan

      Articles written in Proceedings – Section B

    • Effect of insulin on carbohydrate metabolism of the bivalve molluscMeretrix casta (chemnitz)

      S Kasinathan

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      The effect of injection of insulin intoMeretrix casta has been investigated. Insulin lowers the blood glucose level significantly after an hour following the injection; recovery sets in later. Increase of dosage of insulin produces increased lowering of blood glucose.

      Injection of insulin produces an increase of glycogen content in the digestive diverticula and foot but there is a differential effect of insulin on the glycogen content of digestive diverticula and foot. The former seems to be a labile storehouse of carbohydrates and the latter a more stable store, with probably some mechanism of regulation.

    • A study of alloxan-induced “diabetes” in the estuarine clam,Meretrix casta (Chemnitz)

      S Kasinathan

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      1. Effects of different concentrations of alloxan on the blood glucose and tissue glycogen levels of the estuartine clam,Meretrix casta (Chemnitz), have been investigated.

      2. In alloxan-diabetic specimens, there is an increase in the glycogen content in the foot and digestive diverticula. The overall increase and the range of fluctuations was greater in the digestive diverticula.

      3. Alloxan shows a differential effect on the quantity of glycogen in the tissues.

      4. Alloxan effect onMeretrix casta is different from toxic and cold effects on the glycogen content.

    • Seasonal variation and exogenous hormonal effect on the interrenal glands ofRana hexadactyla lesson

      S Kasinathan S L Basu

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      Seasonal variation of the interrenal cell-types both in male and femaleRana hexadactyla and the exogenous hormonal effects on the male interrenals have been studied quantitatively. The interrenal cell-types wax and wane throughout the year. A reciprocal relation between the clear and compact cells of the interrenal in both sexes of the frogs has been observed.

      The decrease of compact cells and regression of interrenal activity resulting from steroid administration were found to be statistically significant. Concomitant with the decrease of interrenal activity, a regression of interstitium of testis has been noticed.

      Pituitary administration stimulates interrenal activity accompanied by an increased spermatogenesis.

      A possible role of exogenous steroid and pituitary hormones on the interrenal has been discussed.

    • Steroids in the interrenal and gonads of some amphibians andCalotes—A chromatographic study

      S Kasinathan S L Basu

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      The gonadal and interrenal steroid ofRana hexadactyla, Rana cyanophlyctis, Rhacophorus maculatus andCalotes versicolor have been analysed by paper chromatography. In the interrenal of both the sexes of three species of frogs studied, aldosterone and corticosterone could be detected. In the testes of all the three species of frogs studied, testosterone was significantly absent; progesterone and 17β estradiol were detected. In the ovary 17β estradiol. estriol and progesterone were identified. In the adrenals ofCalotes, as in frogs, corticosterone and aldosterone were noticed. In the testis testosterone and 17β estradiol were detected; in the ovary progesterone, estriol, estrone and 17β estradiol were found. The significance of the presence of testosterone and the absence of progesterone in the testes is discussed in the light of biosynthetic pathway known in other forms.


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