V M Thakor
Articles written in Proceedings – Section A
Volume 37 Issue 6 June 1953 pp 765-773
In extension of the previous work1, 2 Friedel and Crafts acylation has been studied with 4-nitroresorcinol. 4-Nitroresorcinol on Friedel-Crafts acetylation furnished 2: 6-dihydroxy-3-nitroacetophenone along with small amounts of the known 5-nitroresacetophenone, substitution occurring mainly in the γ-position. 4-Nitroresorcinol-l-methyl ether similarly gave 2-hydroxy 3-nitro-6-methoxyacetophenone as the sole product. Similar γ-substitution was observed on Friedel-Crafts propionylation, butyrylation and benzoylation of 4-nitroresorcinol. The constitutions in all the cases have been established by comparing with the products of nitration of the corresponding 2-acylresorcinols. This observation furnishes further proof of existence of chelation in 4-nitroresorcinol resulting in the preferential substitution in the γ-position.
Volume 37 Issue 6 June 1953 pp 774-783
Kostanecki-Robinson reaction has been studied with various
Volume 38 Issue 1 July 1953 pp 31-39