K S R Krishna Mohan Rao
Articles written in Proceedings – Section A
Volume 67 Issue 1 January 1968 pp 42-49
A number of 3-amino-4-hydroxy coumarins substituted in the benzene ring have been synthesised by two methods starting from 4-hydroxy coumarins, one by nitration and reduction, and the other by diazotisation-coupling and reduction. The amino hydroxy coumarins have been converted into the corresponding (3 : 4) oxazoles by condensation with aromatic aldehydes. The ultraviolet and infrared spectral data as well as their bacteriostatic and fungistatic properties are presented.
Volume 69 Issue 2 February 1969 pp 88-93
The synthesis of a few (7, 8) oxazolo-flavones has been carried out starting from 7-hydroxy-8-amino flavone. The ultraviolet and infrared spectra of these new class of heterocyclic compounds have been studied. The anti-bacterial and anti-fungal activities of these compounds have been reported.
Volume 69 Issue 6 June 1969 pp 289-289 Erratum
Volume 77 Issue 4 April 1973 pp 149-156
A few isoxazolo (7, 8-
Volume 81 Issue 6 June 1975 pp 262-270
A novel method of establishing the direction of enolization of a 1:3-diketone is to examine of the mass spectrum of the isoxazole obtained from it by hydroxylamine treatment. Thus, the products obtained from five 1:3 diketones,
Volume 84 Issue 2 August 1976 pp 79-84
3 : 5-Dimethyl-4-nitro isoxazole and 3-aryl-2-isoxazolin-5-ones were found to undergo the Mannich reaction readily at room temperature, affording in most cases unstable products. While the 5-methyl group was the active site with the former, the latter underwent reaction exclusively at the 4-position. The structures of the products were confirmed by spectral data. The Mannich bases from the isoxazolones were found to exist in three tautomeric modifications, contrary to earlier observations. Most of the products exhibited a high degree of antibacterial activity.