G N Vyas
Articles written in Proceedings – Section A
Volume 32 Issue 6 December 1950 pp 386-389
The synthesis of 6-hydroxy-flavonols has been effected by the Algar and Flynn oxidation of 2∶5-dihydroxy-, 2∶5∶2′-trihydroxy-, 2∶5∶4′-trihydroxy-chalkones and 6∶3′-dihydroxy- and 6∶4′-dimethoxy-flavanones by means of alkaline hydrogen peroxide. The flavonols obtained have been characterised by preparing their acetyl or methoxy derivatives. It is interesting to note that free hydroxyl group in either nucleus of the chalkone molecule does not lead to complications during the oxidation, the flavonols being obtained in good yield.
Volume 33 Issue 2 February 1951 pp 112-115
6-Hydroxy-flavones have been synthesised by the Venkataraman oxidation of 2:5-dihydroxy-, 2:5:2′-trihydroxy-, 2:5:4′-trihydroxy chalkones as well as 6:3′-dihydroxy-flavanone by selenium dioxide. Thus the polyhydroxy-chalkones can be oxidised to the corresponding hydroxy-flavones in one step.