A C Mehta
Articles written in Proceedings – Section A
Volume 38 Issue 5 November 1953 pp 381-386
It is established that the condensation of 2-hydroxy-4:6:2′-trimethoxy phenyl benzyl ketone and its 3-methyl derivative with ethyl formate as well as with methyl formate produces the corresponding 2-hydroxy isoflavanones. These undergo dehydration to the trimethyl ether of isogenistein and 8-methyl isogenistein respectively. Demethylation of the above ethers can be conveniently effected by aluminium chloride in benzene solution. The 2-hydroxy isoflavanones also yield the same products by undergoing dehydration along with demethylation.
Volume 42 Issue 4 October 1955 pp 192-194
By the use of ethoxy acetyl chloride and pyridine at 0°, 7-hydroxychromeno-(3′∶4′∶2∶3)-chromone has been synthesised much more conveniently than by the earlier methods reported in the literature.
Volume 45 Issue 1 January 1957 pp 15-19
The position of the methoxyl group in dalbergin has been established by synthesis using two methods: (1) partial methylation of 4-phenyl-aesculetin and (2) nuclear oxidation of 4-phenyl umbelliferone methyl ether. By similar methods the 7-benzyl ether of 4-phenyl aesculetin and from it by methylation and debenzylation iso-dalbergin has been prepared. The ethyl ethers of dalbergin and iso-dalbergin have also been obtained.
Volume 45 Issue 5 May 1957 pp 293-297
Though the benzophenone method of synthesis is not quite advantageous for dalbergin and methyl dalbergin, it is more convenient for the preparation of allo-dalbergin (4-phenyl-5-methoxy-6-hydroxy coumarin) and its methyl ether. These compounds and other 4-phenyl coumarins give markedly coloured solutions when treated with alcohol, hydrochloric acid and magnesium; a number of 4-methyl coumarin derivatives also give similar colour reactions. On the other hand 3-phenyl and 3-phenyl-4-methyl coumarin derivatives do not respond to this test which may therefore be of diagnostic value.