Deoxyribonucleic acid (DNA) is the molecule that carries geneticinformation in a cell. The field of DNA nanotechnologyaims to use DNA as the basis for making complex nanometerscalestructures. While much progress has been made in creatingsuch nano-architectures, the use of these structureswithin organisms had never been attempted. Our work is focusedon using a simple DNA-based pH sensor in worms toyield information about organelle activity in cells. The firstof its kind, this work set up a system to use DNA as a probein living systems.
