Zebrafish, a freshwater teleost fish, is a popular vertebrate model to study embryo development, organogenesis, gene mutations, and adult physiology. Owing to its biological and genetic advantages, zebrafish is a preferred system for toxicological studies, modeling human diseases, and studying innate immunity. Its usage in studying psychosomatic behavioral disorders has been appreciated recently. Zebrafish is an easy-to-culture, non-invasive vertebrate system with potential multidisciplinary utility in undergraduate teaching and research.