The effects of quantum correction on the Rayleigh.Taylor instability (RTI) in stratified plasma layer have been investigated in the presence of suspended particles. A general dispersion relation is obtained from the linearized set of quantum hydrodynamic (QHD) equations. Two particular cases of suspended particle parameters ($f \ast$ and $\alpha_0$) with and without quantum corrections are analysed. The condition of RTI is derived while the stability of the system is discussed by applying Routh.Hurwitz (RH) criterion in the polynomial equation. The results show that, in the absence of quantum term, the relaxation frequency of the suspended particles has a destabilizing effect, while the mass concentration of the suspended particles has a stabilizing effect on the growth rates of RTI. In the presence of the quantum term, the relaxation frequency of the suspended particle yields to the stability behaviour on the growth rates of RTI.