An analytical study to investigate the double diffusive convection in peristaltic pumping of ionic nanofluids through asymmetric microchannel under the influence of electromagnetohydrodynamics (EMHD) is presented. Thermal radiation effect is also considered. Velocity slip and convective boundary conditions are employed at the permeable channel walls. Debye Hückel linearisation is considered to simplify the Poisson–Boltzmann equation. The normalised two-dimensional conservation equations formass, momentum, energy, solutal concentration and nanoparticle fraction are reduced when long wavelength and low Reynolds number are assumed. Analytical solutions are computationally illustrated with MATLAB software to describe the pumping, flow and thermal characteristics under the effects of relevant parameters like Biot number, slip parameters, thermal radiation, Debye length, Hartmann number and Grashof numbers. Furthermore, solutal concentration, nanoparticle fraction and heat transfer coefficient are also analysed to see the influences of pertinent parameters. Such observations may be applicable to develop electro-osmotically actuated bio-microfluidic systems for smart drug delivery andmicrolevel physiological transport.