S. G. Levit
Articles written in Journal of Genetics
Volume 30 Issue 3 May 1935 pp 389-396
Volume 33 Issue 3 December 1936 pp 411-434
1. The majority of pathological genes in man:
are conditionally dominant, showing a definite expression in the heterozygote, and
have poor penetrance. This is true both for autosomal as well as for sex-linked genes.
2. Conditionally dominant genes (in the heterozygote) tend to be expressed later in ontogeny than recessive genes (in the homozygote).
3. An explanation is given for these phenomena from the point of view of the evolution of dominance.
Volume 35 Issue 2 November 1937 pp 151-159
The present paper points out the incorrectness of conclusions in human genetics when based on literary selection.
To avoid this, a method is used by which material may be genetically analysed, sporadic cases being completely ignored. Pettersson & Bonnier’s data on a form of hermaphroditism is analysed according to this method. By selecting exclusively familial cases from the literature and applying an incorrect method of genetical analysis, these authors naturally obtained a surplus of affected sibs, and to explain this surplus proposed improbable hypotheses. The same data analysed according to the method here proposed gave very close agreement between the expected and obtained number of affected individuals.
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