Articles written in Journal of Genetics
Volume 26 Issue 1 July 1932 pp 129-142
The somatic chromosome complements of sixty-four species and varieties of
Hybridisation and polyploidy.
Fragmentation and possibly fusion.
Genotypic change controlling bulk and width of the chromosomes.
The occurrence of certain species with an odd somatic number of chromosomes shows that clouai propagation must have been comparatively extensive.
Finally a comparison between
Volume 27 Issue 2 May 1933 pp 243-259
Various genetical data on diploid and triploid
It is shown that the frequencies of crossing-over in the diploid agree with the cytologically observed frequencies of chiasma formation and persistence in other organisms, so lending support to the partial chiasma-type hypothesis. The various types of interference are discussed.
The behaviour of the chromosomes at pachytene (synapsis) in the triploid is deduced and it is shown to agree with the cytologically observed behaviour of chromosomes in certain plants. It is also shown that non-random disjunction of the chromosomes may occur in a triploid and its genetical consequences are pointed out.
Volume 28 Issue 1 October 1933 pp 1-24
Volume 30 Issue 1 January 1935 pp 53-78
Volume 32 Issue 2 April 1936 pp 287-314
Volume 33 Issue 2 October 1936 pp 207-235
Volume 39 Issue 2 January 1940 pp 205-223
The positions of chiasmata at metaphase are dependent on (
A method is given for determining the mean positions of formation of chiasmata relative to the centromere and to one another, by comparison between the size classes in organisms with a large chromosome size range. The original positions as determined in this way seem to be retained at metaphase. There is thus no need to suppose that interstitial chiasmata have moved between their formation and the attainment of metaphase.
Thus terminalization is an all or none process. Either all the chiasmata terminalize or they do not move, except for occasional movement of the most distal chiasma to the end of the bivalent as a result of absorption of the free distal arm.
Some properties of chiasma formation in two-armed chromosomes are discussed and certain observations which would be critical for the hypothesis of centromeric determination of the position of chiasmata are described.
Volume 40 Issue 1-2 May 1940 pp 229-241
The gene umbrous is a modifier of the expression of agouti. It has no visible effect in non-agouti animals, but makes agouti mice darker. Heterozygous agouti is affected more than homozygous agouti. Heterozygous umbrous has a definite effect, but it is not so marked as that of homozygous umbrous. In homozygous umbrous mice, homozygous and heterozygous agouti animals are separable by eye, whereas in nonumbrous mice they are not. Hence umbrous may be regarded as a dominance modifier of agouti.
Umbrous appears to act by controlling the rate or degree of progress of the reaction or reactions whose occurrence is determined by the agouti gene.
Dominance is a character subject to selective control, acting directly through the difference in phenotype of the heterozygote and homozygote, rather than indirectly through a correlation of degree of dominance and variability of the homozygote.
Volume 41 Issue 2-3 January 1941 pp 159-193
Volume 43 Issue 1-2 January 1942 pp 1-30
The usual type of genetic experiment utilizes only one of the four spores resulting from meiosis in a mother cell. In some organisms it is possible to make a genetical analysis of all four spores, and such analyses will yield considerably more information about linkage of two genes, or of gene and centromere, than does the common type of genetical experiment. The observations made on different spores of the same tetrad are, however, not independent but the problems of estimation which arise may be overcome by the method of maximum likelihood.
Estimation of the recombination fraction and its variance from completely and incompletely analysed tetrads with and without viability disturbances is considered. The relative values of the various types of data are given, and the appropriate method of combining them in a single estimation is also given. Special attention is paid to the cases of close linkage of two genes, and linkage of a gene to the centromere.
The calculation of coincidence values and their variances is discussed.
Many of the calculations are illustrated arithmetically, using data from segregation in
Volume 43 Issue 3 April 1942 pp 309-336
Volume 45 Issue 3 December 1943 pp 215-235
Volume 45 Issue 3 December 1943 pp 243-260
Volume 46 Issue 1 April 1944 pp 52-61
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