• D. K. Uppal

      Articles written in Journal of Genetics

    • Interference by recessive lethals in the re-isolation of a translocation homozygote inAedes aegypti

      D. K. Uppal C. F. Curtis

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      A reciprocal translocation between chromosome 2 and 3, designated T2, was viable when homozygous in the ROCK strain ofAedes aegypti. It was backcrossed five times with Delhi wild type material. Despite intensive efforts it was not possible to re-isolate it as a homozygote, indicating that a factor in the Delhi background interacted with the translocation and caused recessive lethality. In certain families inbreeding without the production of genetically marked non-translocation homozygotes suggested that a translocation homozygote line had been isolated but, when outcrossed, all the individuals were found to be translocation heterozygotes. It was shown that a balanced lethal system existed which maintained permanent translocation heterozygosity in this line.

    • Simulation of alternative genetic control systems forAedes aegypti in outdoor cages and with a computer

      C. F. Curtis N. Lorimer K. S. Rai S. G. Suguna D. K. Uppal S. J. Kazmi E. Hallinan K. Dietz

      More Details Abstract Fulltext PDF

      Cycling populations ofA. aegypti of wild origin were established in outdoor cages. Releases were then made for 32–43 days of either males carrying chromosome translocations or males of the sex ratio distorter type. The translocation caused a maximum of 50% sterility, but this declined rapidly after termination of releases. The distorter males depressed the proportion of females among the pupae produced in the cage to a minimum of 35% and the distortion of sex ratio persisted for 13 weeks following termination of releases. It was pos sible to simulate the effects of the releases with a computer. Simulations were also made of standard release schedules of three types of genetic material. A strain carrying both sex ratio distortion and a translocation gave the most effective population suppression.

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