Bing-Jian Feng
Articles written in Journal of Genetics
Volume 81 Issue 3 December 2002 pp 99-103
Yin Y. Shugart Bing-Jian Feng Andrew Collins
We have evaluated the power for detecting a common trait determined by two loci, using seven statistics, of which five are implemented in the computer program SimWalk2, and two are implemented in GENEHUNTER. Unlike most previous reports which involve evaluations of the power of allelesharing statistics for a single disease locus, we have used a simulated data set of general pedigrees in which a twolocus disease is segregating and evaluated several nonparametric linkage statistics implemented in the two programs. We found that the power for detecting linkage using the Sall statistic in GENEHUNTER (GH, version 2.1), implemented as statistic
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