• ADEGA F

      Articles written in Journal of Genetics

    • LINE-1 distribution in six rodent genomes follow a species-specific pattern

      VIEIRA-DA-SILVA A ADEGA F GUEDES-PINTO H CHAVES R

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      L1 distribution in mammal’s genomes is yet a huge riddle. However, these repetitive sequences were already found in all chromosomicregions, and in general, they seem to be nonrandomly distributed in the genome. It also seems that after insertionand when they are not deleterious, they are always involved in dynamic processes occurring on that particular chromosomicregion. Furthermore, it seems that large-scale genome rearrangements and L1 activity and accumulation are somehow interconnected.In the present study, we analysed L1 genomic distribution in Tatera gambiana (Muridae, Gerbillinae), Acomys sp.(Muridae, Deomyinae), Cricetomys sp. (Nesomyidae, Cricetomyinae), Microtus arvalis (Cricetidae, Arvicolinae), Phodopusroborovskii and P. sungorus (Cricetidae, Cricetinae). All the species studied here seems to exhibit a species-specific pattern.Possible mechanisms, and processes involved in L1 distribution and preferential accumulation in certain regions are discussed.

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