Articles written in Journal of Chemical Sciences
Volume 104 Issue 1 February 1992 pp 57-60 Physical and Theoretical
Syntheses of (4E,6E,11Z)-4,6,11-hexadecatrienyl acetate (
Volume 126 Issue 6 November 2014 pp 1841-1847 Regular Articles
A short, facile and efficient synthesis of D-lyxo-phytosphingosine analogue has been achieved. The key steps involved are the Baylis-Hillman reaction of (S)-Garner aldehyde with methyl acrylate to obtain the corresponding adduct as the potential substrate, to which was added decylmagnesium bromide to obtain the E-trisubstituted alkene followed by OsO4/NMO mediated dihydroxylation gave the desired D-lyxophytosphingosine analogue intermediate diol which on acid hydrolysis resulted in the formation of the target molecule in good yield.
Volume 135, 2023
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