VARADARAJ BHAT
Articles written in Journal of Chemical Sciences
Volume 133 All articles Published: 7 April 2021 Article ID 0035
Use of convertible isocyanides for the synthesis of benazepril hydrochloride
BHUSHAN B BORASE HIMANSHU M GODBOLE GIRIJ P SINGH PRITESH R UPADHYAY ANURAG TRIVEDI VARADARAJ BHAT GAUTHAM G SHENOY
Herein, we have described a novel and concise synthesis of the potent angiotensin-convertingenzyme (ACE) inhibitor, benazepril hydrochloride (7) in trifluoroethanol
Synopsis: An efficient synthesis of benazepril hydrochloride using Ugi three-component reaction.
Volume 134 All articles Published: 20 April 2022 Article ID 0056
The synthesis of sutezolid and eperezolid using proline catalyzed α-aminoxylation of an aldehyde
PANKAJ R CHAUDHARI NANDU B BHISE GIRIJ P SINGH VARADARAJ BHAT GAUTHAM G SHENOY
The given article describes the synthesis of 2-Oxazolidinone ring
Selective α-aminoxylation was achieved on corresponding aldehyde with great enantiomeric excess to get intermediate (5) using catalytic amount of low cost proline. The oxazolidinone ring was then constructed on common intermediate (5) which was then further converted to Oxazolidinone class compounds like Sutezolid and Eperezolid.
Volume 135, 2023
All articles
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode
© 2022-2023 Indian Academy of Sciences, Bengaluru.