The lowestS1(n, π*) transition (absorption) of indanetrione having acis-vicinal triketo group exhibits a large blue-shift in cyclic saturated ethers compared to that in an open-chain saturated ether. This transition of indanetrione in mixed solvents containing a cyclic saturated ether (tetrahydrofuran, dioxane and tetrahydropyran) as one of the components and a non-polar or less polar solvent as the other component has been studied at room temperature. The spectra are also studied in pure cyclic saturated ethers as a function of temperature. These studies suggest a specific interaction between indanetrione and cyclic ethers in the ground state. Similar studies in open-chain saturated ethers indicate the absence of such an interaction. The nature of the specific interaction has been discussed.