Two chiral diamines ($3S$)-3-anilinomethyl-1,2,3,4-tetrahydroisoquinoline (1) and ($2R$)-2-anilinomethylpiperidine (2) have been employed as chiral catalytic sources in the borane-mediated asymmetric reduction of prochiral ketones thus providing the resulting secondary alcohols in good enantiomeric purities (up to 81% $ee$).
Journal of Chemical Sciences
Volume 135, 2023 All articles Continuous Article Publishing mode
