Articles written in Journal of Chemical Sciences
Volume 129 Issue 9 September 2017 pp 1423-1430 Regular Aricle
Anewrhodamine-based Schiff base (L) has been synthesized and characterized by physicochemical and spectroscopic tools. This organic molecule selectively reacts with Cu²⁺ ions with a remarkably significant optical change, which supports the development of a chemosensor for Cu²⁺ ions as low as nanomolar level in aqueous medium. On the basis of the experimental work, the ‘turn-on’ colorimetric/fluorimetric spectroscopic change is due to Cu²⁺ ion-assisted hydrolysis followed by spirolactam ring opening of the probe (L) in 20mM HEPES buffer [pH 7.4; water/acetonitrile (9:1 v/v)]. The competitive ions do not affect the selectivity and specificity of the probe (L) in the detection of Cu²⁺ ions. The cell imaging study using fluorescence microscope showed that this non-cytotoxic probe is useful to detect the distribution of Cu²⁺ ions in AGS cells lines.
Volume 134, 2022
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