• RODOLFO QUEVEDO

      Articles written in Journal of Chemical Sciences

    • Ninhydrin reaction with phenylethylamine: unavoidable by-products

      ANDRE´S GONZALEZ-ONATE RODOLFO QUEVEDO

      More Details Abstract Fulltext PDF

      Ninhydrin and phenylethylamine reacted to form a complex mixture from which four products were isolated: a benzo-fused spiroheterocyclic and a pyrrole product resulting from tricomponent condensation between ninhydrin, phenylethylamine and phenylacetaldehyde produced in situ, a 2-amino-1,3-indandione dimerisation-dehydrogenation product and a Schiff base. This article analyses these compounds’ structure and proposes reaction mechanisms contributing to knowledge regarding ninhydrin and phenylethylamine chemical reactivity.

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