Articles written in Journal of Chemical Sciences
Volume 97 Issue 1 July 1986 pp 91-95 Physical and Theoretical
The estrogen receptor binding affinity of 2-phenylindoles is found to be significantly correlated with Kier’s first-order valence molecular connectivity index. The correlation equations obtained provide a much simple rationale to design more potent compounds and help in predicting the potency of new compounds.
Volume 133 All articles Published: 7 April 2021 Article ID 0035
Herein, we have described a novel and concise synthesis of the potent angiotensin-convertingenzyme (ACE) inhibitor, benazepril hydrochloride (7) in trifluoroethanol
Synopsis: An efficient synthesis of benazepril hydrochloride using Ugi three-component reaction.
Volume 134 All articles Published: 20 April 2022 Article ID 0056
The given article describes the synthesis of 2-Oxazolidinone ring
Selective α-aminoxylation was achieved on corresponding aldehyde with great enantiomeric excess to get intermediate (5) using catalytic amount of low cost proline. The oxazolidinone ring was then constructed on common intermediate (5) which was then further converted to Oxazolidinone class compounds like Sutezolid and Eperezolid.
Volume 134, 2022
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