Articles written in Journal of Chemical Sciences
Volume 133 All articles Published: 20 July 2021 Article ID 0077
Untargeted synthesis leading to the formation of a significant product is a common practiceand has been successfully achieved after holistic characterization of the accidentally formed molecule ofthe trimer of pyrazolone. Its significance was further explored in the pharmaceutical field emphasizing theneed for the synthesis and validating the newly established pathways for its synthesis. It was known thatpyrazolone exhibit a plethora of applications ranging from catalysis, decolourisation of dyes and metallurgicalextractions. Paramount importance has been attributed to pyrazolones in recent years for theirbroad-spectrum biological activities manifested in their anti-inflammatory, analgesic, anticancer and antitubercularfunctions. In the ongoing research 4,4-Bis-(3-methyl-phenyl-pyrozolin-5-on-4-yl)-3-methyl-1-phenyl-pyrzolin-5-one was synthesized economically and efficiently
An investigatory report is being presented featuring a novel eco-friendly pathway for the synthesis of trimeric of pyrazolone i.e., 4,4-Bis-(3-methyl-phenyl-pyrozolin-5-on-4-yl)-3-methyl-1-phenyl-pyrzolin-5-one. The trimeric form of the molecule possesses spiked antioxidant properties verified by DPPH and ABTS assays. Thus, this work opens new frontiers for further research in this direction.
Volume 134, 2022
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