Osmo E O Hormi
Articles written in Journal of Chemical Sciences
Volume 127 Issue 11 November 2015 pp 1937-1943 Articles
Three novel 5-(𝑁-substituted-anilino)-8-benzyloxyquinoline derivatives were efficiently synthesized via Hartwig–Buchwald amination reaction. The new 5-(𝑁-substituted-anilino)-8-benzyloxyquinolines were reduced for 1–3 h to give the corresponding 5-(𝑁-substituted-anilino)-8-hydroxyquinolines. Extending the reduction reaction time to 7 h afforded the corresponding 1,2,3,4-tetrahydro-8-hydroxyquinoline derivatives.
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