MOHAMED BOURASS
Articles written in Journal of Chemical Sciences
Volume 132 All articles Published: 11 July 2020 Article ID 0086
MOHAMMED CHALKHA MOHAMED BAKHOUCH MOHAMED AKHAZZANE MOHAMED BOURASS YOHANN NICOLAS GHALI AL HOUARI MOHAMED EL YAZIDI
In this work, we report the synthesis of new pyrazole derivatives bearing amide and sulfonamide frameworks from aza-aurones. Firstly, the intermediate spiropyrazolines were obtained through a highly regioselective 1,3-dipolar cycloaddition of nitrilimines with aza-aurones. Subsequently, the obtainedcycloadducts were subjected to hydrochloric acid in hot ethanol which conducts to 5-(2-aminobenzoyl)-3,4-diaryl-1-phenylpyrazoles. Finally, the target compounds were obtained separately by the action of acetic anhydride, benzoyl chloride and tosyl chloride on the intermediates 2-aminobenzoylpyrazoles, respectively.Structures of all the synthesized compounds were established using IR, 1H NMR and 13C NMR and mass spectroscopy.
Volume 132, 2020
All articles
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode
© 2021-2022 Indian Academy of Sciences, Bengaluru.