A BINOL accelerated Ru-catalyzed ortho-selective C-H coupling of arenes tethered to 7-azaindoles is described with disulfides and diselenides under air. The thioether can be readily oxidized to sulfoxide and sulfone. The use of less expensive Ru-catalysis, substrate scope and scale-up are the important practical features.
Journal of Chemical Sciences
Volume 135, 2023 All articles Continuous Article Publishing mode
