Vanadium-incorporated molybdophosporic acid catalysts supported on titania were prepared and characterized by FT-IR, X-ray diffraction and laser Raman spectroscopy. Characterization data reveals the incorporation of vanadium into the primary structure of Keggin ion of MPA. Catalysts activities were evaluated for oxidation of 1,2-benzenedimethanol using H₂O₂ and O₂ as oxidants. Vanadium-containing catalysts showed high activity compared to their parent heteropoly acids. Oxidation ability depended on the number of V atoms present in Keggin heteropoly molybdate. Effect of reaction parameters on the oxidation ability was also evaluated.