Articles written in Journal of Chemical Sciences
Volume 88 Issue 5 October 1979 pp 329-335 Organic
The kinetics of reaction between benzyl chloride and phenol (or substituted phenols) in the presence of sodium hydroxide have been investigated. A differential application of the effect of substituents on the reaction rate to distinguish between a rate-limiting oxygen or carbon attack has been attempted. Considerable scatter in the Hammett plot for the latter attack points to an essentially O-alkylation. The rate constants correlate well with pKa values of the different phenols. The influence of salt and solvent on the reaction rate suggests this reaction to be an ion-dipole one.
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