HUIDROM BIRKUMAR SINGH
Articles written in Journal of Chemical Sciences
Volume 132 All articles Published: 20 June 2020 Article ID 0076
PANNEERSELVAM YUVARAJ HUIDROM BIRKUMAR SINGH ARUN PRASATH LINGAM KANDAPALAM DEVARAJAN KATHIRVELAN SANKARANARAYANAN NAGARAJAN
An efficient, atom economical, one-pot synthesis of endo'- selective (dispiro 3,2¢-pyrrolidinyl) bisoxindole containing three contiguous chiral stereocenters with two contiguous quaternary spirostereo centers have been achieved by three-component reaction of isatins, malononitrile (cyanoacetic ester) and 1,3-dicarbonyl compounds in water in the presence of L-proline. One-pot, azomethine ylide cycloaddition with a dipolarophile without using any catalyst have also been achieved in good yields. This new methodology offers many advantages of catalyst-free, mild reaction conditions, shorter reaction time, environmental friendliness, regio- and stereoselective processes in higher yields
Volume 132, 2020
All articles
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode
© 2021-2022 Indian Academy of Sciences, Bengaluru.