HARE RAM YADAV
Articles written in Journal of Chemical Sciences
Volume 128 Issue 11 November 2016 pp 1775-1782 Regular Article
An unprecedented solid of coper(II) complexes [Cu(dpa)₂NCS]₂[Cu(dpa)₂(NCS)₂](ClO₄)₂ (1) [dpa = 2,2'-dipyridylamine; SCN = thiocyanate], has been synthesized and crystallographically characterized with the aim to study the catecholase activity. The Cu(II) complex mimics the full catalytic cycle of the active site of catechol oxidase enzyme in acetonitrile medium with a turnover number of 4.788 × 10³ h⁻¹ along with the production of semiquinone radical and hydrogen peroxide. In situ generation of Cu(I) species in the catalytic pathway of catechol oxidation was established by electrochemical study and further confirmed by electron paramagnetic resonance (EPR) spectroscopy.
Volume 129 Issue 10 October 2017 pp 1513-1520 REGULAR ARTICLE
A mononuclear cobalt(II) complex, [Co(phen) ₂Cl ₂], (phen = 1,10-phenanthroline) has been synthesized and structurally characterized by different spectroscopic methods including single crystal X-ray structural study.X-ray crystal structural analysis revealed that the cobalt(II) complex crystallizes in amonoclinicsystem with C2/c space group and exists in cis-configuration in its crystalline state. Room temperature magnetic measurement accounts for 3e paramagnetism and indicates high spin cobalt(II) in the solid state. The cobalt(II) complex has been evaluated as a functional model for phosphatase enzyme by using 4-nitrophenylphosphate (PNPP) as a standard substrate in aqueous DMF medium. This mononuclear cobalt(II) complex exhibits good hydrolytic phosphoester cleavage efficiency with kcat value of 3.78 × 10 ²h ⁻¹.
Volume 134, 2022
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