Articles written in Journal of Chemical Sciences
Volume 130 Issue 8 August 2018 Article ID 0107
Polyoxometalate entrapped caprolactam gels and their cytotoxicity study
K SHAKEELA G SILPA SURESH KUMAR RAYALA G RANGA RAO
Polyoxometalate (POM) based gels are synthesized by reacting POMs with an excess of caprolactam. These POM-entrapped caprolactam gels are thermoreversible and possess good mechanical strength. The gelation of POMs in caprolactam matrix brought the gel acidity similar to the physiological pH. The cytotoxicity studies on SCC 131 cell lines using these gels show 50% of cell death in the range of 2 to 6 mM concentration in 48 h. The supramolecular caprolactam matrix with active protons and the redox property of POMs are responsiblefor the cytotoxicity effect.
Volume 135, 2023
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