Fenghai Li
Articles written in Journal of Chemical Sciences
Volume 130 Issue 5 May 2018 Article ID 0055
A convenient and novel two-step one-pot method for the synthesis of 3-substituted imidazo[1,2-a]pyridines and 3-substituted imidazo[1,2-b]pyridazines was developed through the reaction of heterocyclic amines and N, N-dimethylformamide dimethyl acetate with active electrophiles RCH2Br (R=CO2Et, CN, COPh, 4'-MeO-PhCO and 4'-F-PhCO). This protocol provides a simple and practical approach to 3-substituted fused imidazo-heterocyclic compounds in moderate to high yields
Volume 135, 2023
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