Fariba Salimi
Articles written in Journal of Chemical Sciences
Volume 125 Issue 5 September 2013 pp 1087-1092
Javad Safaei-Ghomi Fariba Salimi Ali Ramazani
A simple, mild and convenient method has been developed for the synthesis of 3,4,5-trialkyl-1,3-thiazole-2(3𝐻)-thione derivatives through one pot three-component reaction between a primary amine, carbon disulphide, and 𝛼-haloketone in the presence of potassium iodide at room temperature conditions. The products were obtained with excellent yield and appropriate reaction times. This reaction represents a rapid and unprecedented route to the described molecules that have biological specifications.
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