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Journal of Chemical Sciences
Volume 135, 2023
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Continuous Article Publishing mode
C V Nataraj
Articles written in Journal of Chemical Sciences
Volume 87 Issue 1 January 1978 pp 1-12 Organic
C V Nataraj Chitra Mandal P K Bhattacharyya
Specific penicillin-carrier receptor proteins (CRP) have been isolated from the sera of penicillin allergic rabbits and human subjects in the unconjugated native state in electrophoretically homogeneous form by employing a synthetic polymeric affinity template containing the 7-deoxy analogue of penicillin G. The synthesis of the 7-deoxy analogue has been described. In this affinity system the antipenicillin-antibody is desorbed by 0·9M thiourea and the CRP in 8M urea. The CRP after incubation with penicillin is converted into the full-fledged antigen. Studies on the origin of CRP and the nature of antibody as well as comparative studies on the properties of the rabbit antibody and those of antibodies elicited by a BSA-BPO conjugate are reported.
Volume 135, 2023
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Continuous Article Publishing mode
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