Bimal K Bachhawat
Articles written in Journal of Chemical Sciences
Volume 93 Issue 7 September 1984 pp 1111-1115
Dual role of liposomes as adjuvant and carrier for the production of sugar-specific antibodies
Manoj K Das Bimal K Bachhawat Pijush K Das Debi Prasad Sarkar
Aminophenyl derivatives of monosaccharides were coupled to the surface of phosphatidylethanolamine containing liposomes. The glycosylated liposomes elicited in rabbits a hapten-specific immune response. The magnitude of antibody formation was nearly equivalent in the presence and the absence of Freund's adjuvant. The antibody response mediated through liposomes was better than that obtained through the protein carrier.
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