• Amitabh Jha

      Articles written in Journal of Chemical Sciences

    • Potentially useful lipase-catalysed transesterifications

      Amitabh Jha Kirpal S Bisht Virinder S Parmar

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      Organic reactions catalysed by commercially available lipases, reported in recent years from our own laboratory and those published by others are described, confining the discussions to esteriflcation and hydrolytic reactions only. The text gives an insight into the variety of substrates accepted by these lipases and their potential applications to catalyse reactions regio-, chemo-, enantio- and diastereoselectively to produce compounds of industrial, commercial, pharmaceutical and synthetic interest.

    • Chiral discrimination by hydrolytic enzymes in the synthesis of optically pure materials

      Virinder S Parmar Kirpal S Bisht Amarjit Singh Amitabh Jha

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      Enantioselection effected by commercially available hydrolytic enzymes reported in recent years from our own laboratory and those published by other groups is described. The discussion is confined to enantioselection in symmetric diols, amino acids and benzopyran derivatives only. The paper describes a variety of substrates accepted by these hydrolytic enzymes to produce compounds in high enantiomeric excess which can be used as chiral building blocks for the synthesis of compounds of pharmaceutical and synthetic interest.

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