In this paper, diphenyl phosphate creatine was successfully immobilized on Fe3O4 nanoparticles and used as the highly efficient catalyst for the aza-Michael reaction of 5-substituted tetrazole and a,bunsaturated carbonyl. The prepared nanocatalyst was fully analyzed by various techniques such as FouriertransformInfrared Spectroscopy (FT-IR), Field Emission Scanning electron microscope (FE-SEM), Vibrating Sample Magnetometer (VSM), Thermal Gravimetric Analysis (TGA) and X-ray Diffraction (XRD). This procedure possesses numerous advantages such as simple work-up, high yield and short reaction times.
