Articles written in Journal of Chemical Sciences
Volume 128 Issue 9 September 2016 pp 1445-1449 Regular Article
Synthesis and anti-acetylcholinesterase activity of benzotriazinone-triazole systems
SETAREH MOGHIMI FERESHTEH GOLI-GARMROODI HEDIEH PILALI MOHAMMAD MAHDAVI LOGHMAN FIROOZPOUR HAMID NADRI ALIREZA MORADI ALI ASADIPOUR ABBAS SHAFIEE ALIREZA FOROUMADI
An approach for the construction of benzotriazinone-triazole system is described. The synthesis is based on diazonium chemistry and subsequent intramolecular heteroatom-heteroatom bond formation. The introduction of triazole moiety occurred via click reaction catalyzed by nano-sized copper, supported on modified silica mesopore KIT-5 leading to the desired products in excellent yield. Also, in vitro acetylcholinesterase(AChE) inhibitory activities of the target compounds were screened by Ellman’s method.
Volume 135, 2023
Continuous Article Publishing mode
Click here for Editorial Note on CAP Mode