Sung-Hou Kim
Articles written in Journal of Biosciences
Volume 8 Issue 3-4 August 1985 pp 579-592
The conformations and energetics of photodamaged DNA
Energy minimization techniques are used in conjunction with the results of small molecule crystallographic studies on relevant compounds to propose structural models for photodamaged DNAs. Specifically, we present models both for a DNA molecule containing a psoralen photo-crosslink and for a DNA molecule containing a thymine photodimer. In both models, significant distortions of the nucleic acid helix are observed, including kinking and unwinding at the damage site and numerous changes in the backbone torsion angles relative to their standard conformations. Both the torsion angle geometries and the energetics of the models are presented in detail.
Volume 24 Issue S1 March 1999 pp 5-31
F Parak A Ostermann G U Nienhaus Nobuo Niimura William A Eaton Stephen J Hagen Eric R Henry James Hofrichter Gouri Jas Lisa Lapidus Victor Muñoz Chih-chen Wang Abani Bhuyan Javant Udgaonkar Heinz Rüterians Derek N Woolfson M D Finucane J H Lees M J Pandya G Spooner M Tuna Wilma K Olson K V R Chary E Westhof I G Wool C C Correll V I Ivanov S A Bondarenko E M Zdobnov A D Beniaminov E E Minyat N B Ulyanov Dale B Wigley Nobuo Shimamoto Takashi Kinebuchi Hiroyuki Kabata Osamu Kurosawa Masao Washizu Barbara Baird David Holowka H Belrhali P Nollert A Royant J P Rosenbusch E M Landau E Pebav-Peyroula Anil K Lala Patrick R D’Silva Daniela Pietrobon Paolo Pinton Paulo Magalhaes Anna Chiesa Marisa Brini Tullio Pozzan Rosario Rizzuto M Montai Shu-Rong Wang José L Carrascosa B Bhattacharyya Ian A Wilson Dinakar M Salunke Kurt Drickamer Anne Imberty A Surolia Louise N Johnson Michal Neeman S M Prince K McLuskey R J Cogdell K McAuley N W Isaacs G Venturoli F Drepper J C Williams J P Allen X Lin P Mathis R van Grondelle Wolfgang Junge T Tsukihara K Shinzawa-Itoh R Nakashima E Yamashita M J Fei N Inoue T Tomizaki C Peters Libeu S Yoshikawa Patrick Chaussepied Keiichi Namba Marie-France Carlier Fariza Ressacl Valerie Laurent Thomas Loisel Coumaran Egile Philippe Sansonetti Dominique Pantaloni Manju Bansal E W Knapp M G Ullmann A Amadei B L de Groot M A Ceruso M Paci H J C Berendsen A Di Nola V Di Francesco P J Munson J Garnier Sung-Hou Kim Jean-Michel Claverie Ian C P Smith P T Callaghan Bruce Cornell Ratna S Phadke Kazuhiko Kinosita D Goldfarb I Qromov C Shutter I Pecht P Manikandan R Carmieli T Shane David S Moss Clare E Sansom Jeremy K Cockcroft Ian J Tickle Huub C P Driessen J Raul Grigera Ramen K Poddar Charles R Cantor Barry Robson Jean Garnier John Helliwell Sunney I Chan Ronald Rock
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