Articles written in Journal of Biosciences
Volume 46 All articles Published: 20 February 2021 Article ID 0022 Review
Since its emergence as a pneumonia-like outbreak in the Chinese city of Wuhan in late 2019, the novelcoronavirus disease COVID-19 has spread widely to become a global pandemic. The first case of COVID-19in India was reported on 30 January 2020 and since then it has affected more than ten million people andresulted in around 150,000 deaths in the country. Over time, the viral genome has accumulated mutations as itpasses through its human hosts, a common evolutionary mechanism found in all microorganisms. This hasimplications for disease surveillance and management, vaccines and therapeutics, and the emergence ofreinfections. Sequencing the viral genome can help monitor these changes and provides an extraordinaryopportunity to understand the genetic epidemiology and evolution of the virus as well as tracking its spread in apopulation. Here we review the past year in the context of the phylogenetic analysis of variants isolated overthe course of the pandemic in India and highlight the importance of continued sequencing-based surveillance inthe country.
Volume 46, 2020
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