S N A Zaidi
Articles written in Journal of Biosciences
Volume 1 Issue 1 March 1979 pp 75-82
Effect of phospholipase-D on rat kidney mitochondria
S N A Zaidi A C Shipstone N K Garg
Incubation of purified rat kidney mitochondrial fraction with phospholipase-D resulted in the accumulation of phosphatidic acid in the membrane due to the degradation of membrane-bound phosphatidylcholine, -serine and-ethanolamine Simultaneously with the hydrolysis of the phospholipids, cholesterol and protein were released from the mitochondrial membrane into the medium, and binding of Ca2+ by mitochondrial membranes increased. Phospholipase Dtreated mitochondrial fraction exhibited increased swelling
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