Rameshwar Singh
Articles written in Journal of Biosciences
Volume 3 Issue 2 June 1981 pp 125-128
Gurucharan Kaur Rameshwar Singh N Z Baquer
Two key enzymes of gluconeogenesis, glucose-6-phosphatase and fructosp-1-6-diphosphatase, were present in the cerebral hemispheres, the cerebellum and the brain stem of the rat brain. Significant activities of these-enzymes were associated with the particulate fraction.
Volume 6 Issue 3 September 1984 pp 331-336
Gurcharan Kaur Rameshwar Singh N Z Baquer
Changes in the activity of hexokinase and lactate dehydrogenase isoenzymes in the three brain regions and heart were studied in the 6-Aminonicotinamide-treated rats. Drug administration decreased the particulate hexokinase and lactate dehydrogenase activity, but increased the soluble hexokinase
Volume 9 Issue 1-2 September 1985 pp 35-40
Gurcharan Kaur Rameshwar Singh Najma Zaheer Baquer
Changes in the subcellular distribution of hexokinase activity from three brain regions and heart were studied during alloxan induced diabetes. There was an overall decrease in the particulate hexokinase with an increase in the soluble form, after different time intervals of the onset of diabetes. Administration of insulin to the diabetic rats showed a partial counteraction of the enzyme changes. A possible regulation of brain hexokinase by metabolite changes is proposed
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