R Basu
Articles written in Journal of Biosciences
Volume 15 Issue 3 September 1990 pp 145-148
Role of nicotinic acid as modulator of liposomal microviscosity
Using the fluorescent probe 1,6-diphenyl-1,3,5 hexatriene, we have investigated the effect of nicotinic acid, a derivative of the toxic alkaloid nicotine, on the fluidity profile and activation energy of diffusion in the liposomal system of several lipids. We have also studied how the fluidizing property of nicotinic acid affects the intermediate fluid condition induced by cholesterol in these liposomal systems
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