• KUNTAL GHOSH

      Articles written in Journal of Biosciences

    • Computational neuroscience and neuroinformatics: Recent progress and resources

      LOSIANA NAYAK ABHIJIT DASGUPTA RITANKAR DAS KUNTAL GHOSH RAJAT K DE

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      The human brain and its temporal behavior correlated with development, structure, and function is a complex naturalsystem even for its own kind. Coding and automation are necessary for modeling, analyzing and understanding the 86.1 ±8.1 billion neurons, an almost equal number of non-neuronal glial cells, and the neuronal networks of the human braincomprising about 100 trillion connections. ‘Computational neuroscience’ which is heavily dependent on biology, physics,mathematics and computation addresses such problems while the archival, retrieval and merging of the huge amount ofgenerated data in the form of clinical records, scientific literature, and specialized databases are carried out by ‘neuroinformatics’approaches. Neuroinformatics is thus an interface between computer science and experimental neuroscience.This article provides an introduction to computational neuroscience and neuroinformatics fields along with their state-ofthe-art tools, software, and resources. Furthermore, it describes a few innovative applications of these fields in predictingand detecting brain network organization, complex brain disorder diagnosis, large-scale 3D simulation of the brain, brain–computer, and brain-to-brain interfaces. It provides an integrated overview of the fields in a non-technical way, appropriatefor broad general readership. Moreover, the article is an updated unified resource of the existing knowledge and sources forresearchers stepping into these fields.

    • A microscopic study on scattering in tissue section of Alternanthera philoxeroidesunder polarized light

      SHIBSANKAR ROY BARNINI BHATTACHARYA BIJAY BAL KUNTAL GHOSH

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      Like any other biological tissue, plant tissue also exhibits optical properties like refraction, transmission,absorption, coloration, scattering and so on. Several studies have been conducted using different parts of plantssuch as leaves, seedlings, roots, stems and so on, and their optical properties have been analyzed to study plantphysiology, influence of environmental cues on plant metabolism, light propagation through plant parts and thelike. Thus, it is essential to study in detail the optical properties of several plant parts to determine theirstructural relationship. In this backdrop, an experimental study was conducted to observe and analyze theoptical properties of node and inter-nodal tissue cross-sections of the plant Alternanthera philoxeroides under apolarizing microscope constructed and standardized in the laboratory. The observed optical properties of themicroscopic tissue sections have been then studied to determine a significant structural relationship betweennodal and inter-nodal tissue arrangement patterns as a whole. Tissue sections that have undergone a sort ofbiological perturbation like loss of water (dried in air for 15 min) have also been studied to study the change inthe pattern of tissue optical property when compared with that of normal plant-tissue cross-sections under apolarizing microscope. This type of biological perturbation was chosen for the study because water plays animportant role in maintenance of the normal physiological processes in plants and most other forms of life.

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