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KRISHNAPURA SRINIVASAN
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Volume 42 Issue 4 December 2017 pp 603-611 Article
Uptake of phenolic compounds from plant foods in human intestinal Caco-2 cells
GAVIRANGAPPA HITHAMANI DHANYA KIZHAKAYIL KRISHNAPURA SRINIVASAN
In continuation of our studies on the bioaccessibility of phenolic compounds from food grains as influenced by domesticprocessing, we examined the uptake of phenolics from native/sprouted finger millet (Eleucine coracana) and green gram(Vigna radiata) and native/heat-processed onion (Allium cepa) in human Caco-2 cells. Absorption of pure phenoliccompounds, as well as the uptake of phenolic compounds from finger millet, green gram, and onion, was investigated inCaco-2 monolayer model. Transport of individual phenolic compounds from apical compartment to the basolateral compartmentacross Caco-2 monolayer was also investigated. Sprouting enhanced the uptake of syringic acid from both thesegrains. Open-pan boiling reduced the uptake of quercetin from the onion. Among pure phenolic compounds, syringic acidwas maximally absorbed, while the flavonoid isovitexin was least absorbed. Apparent permeability coefficient P(app) ofphenolic compounds from their standard solutions was 2.02 X 10-6 cm/s to 8.94 X 10-6 cm/s. Sprouting of grainsenhanced the uptake of syringic acid by the Caco-2 cells. Open-pan boiling drastically reduced the uptake of quercetin fromthe onion. The permeability of phenolic acids across Caco-2 monolayer was higher than those of flavonoids.
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Journal of Biosciences
Volume 48, 2023
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Continuous Article Publishing mode
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Journal of Biosciences | News
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To trigger further research on plant mitochondria, the Journal of Biosciences is bringing out a special issue titled "Plant Mitochondria: Properties and Interactions with Other Organelles".
Plant mitochondria are quite distinct and have unique features, such as a cyanide-insensitive alternate pathway. They also interact with chloroplasts to optimize photosynthetic carbon assimilation.
Submissions are welcome until 30 July 2023. The contributions can be original articles, short communications, reviews, or mini-reviews on any topic related to plant mitochondria.
Authors can submit their articles online at https://www.editorialmanager.com/jbsc/default2.aspx
Posted on April 12, 2023< -
Editorial Note on Continuous Article Publication
Posted on July 25, 2019Click here for Editorial Note on CAP Mode
Forthcoming Special issue.
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