• K L Mukherjee

      Articles written in Journal of Biosciences

    • Fructose-1, 6-bisphosphatase in human fetal brain and liver during development

      Tapas Biswas Arun Lahiri Majumder Gitanjali Guha Thakurta K L Mukherjee

      More Details Abstract Fulltext PDF

      Activity of fructose-1,6-bisphosphatase (EC 3.1.3.11), one of the key gluconeogenic enzymes, was measured in human fetal brain and liver during development. Fructose-1,6-bisphosphatase was distributed throughout the different regions of the brain. In contrast to the partially purified enzyme from the brain, the liver enzyme was dependent on Mg2+ for maximal activity, EDTA, citrate, oleate and linoleate were stimulatory, whereas 5′-AMP inhibited the activity of the liver enzyme.

    • Glycosaminoglycans in human fetal liver in relation to water and electrolytes

      Chameli Ganguly K L Mukherjee

      More Details Abstract Fulltext PDF

      The acidic mucoPolysaccharides secreted into the extracellular sPace are thought to Play many imPortant functions amongst which are binding of water and electrolytes on the Polyanionic glycosaminoglycans. Characteristically these comPonents undergo continuous changes during growth and develoPment of the fetuses. RelationshiPs of the concentrations of glycosaminoglycans to the water and PrinciPal electrolytes at different Periods of gestation were studied in human fetuses. It was found that during growth of the human fetuses there was a Progressive decrease in water, thiocyanate sPace, total sodium content and glycosaminoglycans. However the decrease of glycosaminoglycans was greater than the rate of decrease of the other constituents. Hence mucoPolysaccharides were thought to Play more imPortant roles than just binding of water and cations.

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