Articles written in Journal of Biosciences
Volume 38 Issue 2 June 2013 pp 363-371 Articles
Short-term hypoxia/reoxygenation activates the angiogenic pathway in rat caudate putamen
F Molina A Rus Ma Peinado ML del Moral
In response to hypoxia, tissues have to implement numerous mechanisms to enhance oxygen delivery, including the activation of angiogenesis. This work investigates the angiogenic response of the hypoxic caudate putamen after several recovery times.
These results reveal that not only short-term hypoxia, but also the subsequent reoxygenation period, up-regulate the angiogenic pathway in the rat caudate putamen as a neuroprotective mechanism to hypoxia that seeks to maintain a proper blood supply to the hypoxic tissue, thereby minimizing the adverse effects of oxygen deprivation.
Volume 48, 2023
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