• ERNEST DAVID

      Articles written in Journal of Biosciences

    • Biopolymers augment viral vectors based gene delivery

      BALAJI BALAKRISHNAN ERNEST DAVID

      More Details Abstract Fulltext PDF

      The success of viral vectors mediated gene therapy is still hampered by immunogenicity and insufficient transgeneexpression. Alternatively, non-viral vectors mediated gene delivery has the advantage of low immunogenicity despiteshowing low transgene expression. By carefully considering the advantages of each approach, hybrid vectors are currentlybeing developed by modifying the viral vectors using non-viral biopolymers. This review provides an overview of thehybrid vectors currently being developed.

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